Nociceptors can have proton ion channels {acid-sensing ion channel} (ASIC).
Nociceptors and other neurons have special calcium-ion channels {N-type calcium channel} {calcium channel, N-type}. Ziconotide (Prialt), modified cone-snail venom, inhibits N-type calcium channels to lessen pain. Gabapentin (Neurontin) anticonvulsant binds to N-type calcium channels.
Outside CNS, nociceptors and other neurons have special sodium-ion channels {TTX-resistant voltage-gated sodium channel}.
Nociceptors and all neurons have sodium-ion channels {voltage-gated sodium channel} {sodium channel, voltage-gated} that open by voltage changes.
1-Consciousness-Sense-Pain-Anatomy
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Date Modified: 2022.0225